We are looking for dedicated professionals who thrive on tackling complex challenges and are committed to improving the lives of patients. If you value innovation, collaboration, and integrity, and are eager to contribute to advancing therapies for renal diseases, we encourage you to join our team. Based in the state-of-the-art Bakar Labs in Berkeley, CA, we are focused on pioneering medicines that make a meaningful impact.
We are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting research efforts, with a focus on rodent studies, animal colony management, and evaluating novel therapeutics in vivo. As programs advance towards in vivo proof of concept, you will collaborate with scientists to support preclinical evaluations using rodent models. You will manage animal colonies, assist with experimental design, and execute hands-on tasks related to in vivo research.
What You'll Do
- Collaborate with scientists to evaluate novel therapeutic candidates using transgenic mouse models, including target validation and mechanism of action studies.
- Oversee and maintain mouse colonies, including breeding, genotyping, colony expansion, and accurate inventory tracking of vivarium supplies.
- Perform routine in vivo tasks, including animal handling, dosing (oral, IV, IP, SC), blood and tissue collection, sample processing, anesthesia administration, and euthanasia.
- Monitor animal health, maintain compliance with IACUC protocols, and ensure ethical standards in animal care.
- Contribute to experimental design and execution of in vivo studies to support drug discovery programs.
- Provide detailed documentation of experimental protocols, observations, and results.
- Collaborate with multidisciplinary teams, contributing to discussions on in vivo models and study outcomes.
- Adapt to the evolving needs of the team and contribute to maintaining aggressive project timelines.
What You'll Bring
- B.S. degree in a relevant scientific field with 2+ years of hands-on experience in preclinical research or a bachelor’s degree with equivalent relevant experience. Industry experience is advantageous but not required.
- In Vivo Expertise: Proficiency in rodent handling, dosing techniques (e.g., IV, IP, SC), blood and tissue collection, and surgical techniques.
- Mouse Colony Management: Demonstrated experience in managing transgenic mouse colonies, including breeding, genotyping, and maintenance.
- Laboratory Skills: Experience with in vivo sample processing and preparation for downstream assays such as histology or molecular analyses.
- Team Collaboration: Strong interpersonal skills with the ability to work collaboratively in a multidisciplinary environment.
- Communication Skills: Commitment to reporting activities accurately and in a timely manner; keeping open communication with team members to adapt to a fast-paced environment.
- Organization: Exceptional attention to detail, organizational skills, record keeping, and the ability to manage multiple tasks efficiently.
- Commitment to Safety: Adherence to laboratory safety and ethical standards in animal research.
- Flexibility: Willingness to adapt to team priorities and timelines.
We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
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